Ventricular Septal Defect (V.S.D.) Occlusion by AMVO

What is a ventricular septal defect (VSD)?

A congenital defect occurring in the ventricular septum, the wall separating the lower chambers of the heart known as ventricles, is known as the ventricular septal defect. As a result oxygen-rich red blood passes from the left ventricle, through the opening in the septum, and then mixes with oxygen-poor blue blood in the right ventricle. If not treated, this can lead to lung disease due to a larger volume of blood passing from the right ventricle through the pulmonary artery into the lungs, thereby causing higher pressure than normal in the blood vessels in the lungs.

What is a VSD occlusion and what is an AMVO?

VSD occlusion is a method currently being used to close some VSDs through the use of a device called a septal occluder. An AMVO or an AMPLATZER Membranous VSD Occluder is a percutaneous, transcatheter occlusion device intended for occlusion of significant perimembranous ventricular septal defects (VSD) in the membranous ventricular septum. It is a self-expandable, double disc device made from a Nitinol wire mesh.

How is the procedure done?

  • The patients receive a dose of an appropriate antibiotic (commonly Cephazolin at 20mg/kg) during the catheterization procedure)
  • The child is sedated and a small, thin flexible tube is inserted into a blood vessel in the groin and guided into the heart.
  • Once the catheter is in the heart, the cardiologist will pass the septal occluder into the VSD.
  • The septal occluder closes the ventricular septal defect providing a permanent seal.


Panel Of Specialist

Dr. Zainal Hamid

Dr. N. Arunachalam
MBBS, FRCS (Edin), AM (Mal)